Fig. 4.

CSF p-tau205 and p-tau202 association with tau pathology measured by tau-PET (TRIAD cohort). a CSF p-tau205 and b CSF p-tau202 correlated with global tau-PET SUVRs across all cases and CSF Aβ+ participants. c CSF p-tau205 and d CSF p-tau202 displayed regional associations with tau-PET. Data information: Participants colour-coded based on the presence (red) or absence (blue) of CSF amyloidosis measured with Lumipulse CSF Aβ42/40. Spearman’s rank correlation is displayed for all participants, CSF Aβ+ and Aβ- groups. Simple linear regression with 95% confidence intervals of CSF Aβ+ and Aβ− groups is also presented. Voxel maps display the adjusted R-squared and t values of the linear associations between CSF biomarkers and [18F]MK6240, adjusted by age and sex