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. 2023 Sep 29;203(1):163–172. doi: 10.1007/s10549-023-07094-9

Table 2.

Tumor and patient characteristics of the analyzed samples

n = 1049 Prosigna® molecular subtype
Luminal A Luminal B HER2-enriched Basal-like
n = 679 % n = 350 % n = 8 % n = 12 %
Age at diagnosis (years)
 < 50 211 31 74 21 3 38 5 42
 > 50 459 68 271 77 5 63 7 58
 Na 9 1 5 1 0 0 0 0
Tumor type
 Ductal 522 77 293 83 7 88 11 92
 Lobular 110 16 29 8 0 0 0 0
 Others 31 5 19 5 0 0 1 8
 Na 16 2 9 3 1 13 0 0
Tumor size (mm)
 ≤ 20 536 79 234 67 6 75 10 83
 > 20 143 21 116 33 2 25 2 17
ER
 Positive 676 100 350 100 8 100 8 67
 Negative 1 0 0 0 0 0 4 33
 Na 2 0 0 0 0 0 0 0
PR
 Positive 611 90 324 92 5 63 8 67
 Negative 66 10 26 7 3 38 4 33
 Na 2 0 0 0 0 0 0 0
Ki67 index (%)
 < 14 399 59 69 20 0 0 0 0
 14–20 189 28 119 34 1 13 0 0
 > 20 91 13 162 46 7 88 12 100
Ki67 index (%)
 < 13 392 58 64 18 0 0 0 0
 > 13 287 42 286 81 8 100 12 100
Histological grade
 1 81 12 12 3 0 0 0 0
 2 379 56 177 50 1 13 2 17
 3 25 4 53 15 2 25 6 50
 Na 194 29 109 31 5 63 4 33
Prosigna ROR
 Low 461 68 1 0 0 0 1 8
 Intermediate 194 29 145 41 1 13 9 75
 High 24 4 204 58 7 88 2 17
Lymph nodes
 0 521 77 286 82 7 88 10 83
 1–3 158 23 64 18 1 13 2 17

NA non-available, ER estrogen receptor, PR progesterone receptor, HER human epidermal growth factor receptor 2, ROR risk of recurrence