Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2024 Jan 6;8:6. doi: 10.1038/s41698-023-00493-7

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© This is a U.S. Government work and not under copyright protection in the US; foreign copyright protection may apply 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 6 — a, b Simple Western immunoblot analysis showing expression of NICD in PLK1-modulated melanoma cells. The relative protein levels normalized to total protein are presented as bar graphs. c, d Relative mean intensity analyzed by immunofluorescence analysis for nuclear localization OF NOTCH (NICD) in PLK1-modulated melanoma cells. The data are presented as mean ± SEM with statistical significance compared to shNS or pcDNA control (*p < 0.05; ****p < 0.0001) in ≥2 biological replicates. For a, c and d, statistical significance was determined via multiple t-tests using the Holm–Sidak method. For b, statistical significance was determined using one- or two-way ANOVA followed by Fisher’s LSD tests.