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. 2024 Jan 6;15:6. doi: 10.1007/s12672-024-00858-9

Table 2.

Toxicities of compounds

Molecule U.S. National Toxicology Program (NTP) Ames DTP
Mouse/Female Mouse/Male Rat/Female Rat/Male
Fadraciclib 1 1 0 0 0.011 1
Flavopiridol 0.001 1 0 0.474 1 1
P129 1 0 1 1 0 0

Ames < 0.3 (nonmutagen); > 0.8 (mutagen)

DTP (developmental toxicity potential) < 0.3 (nontoxic); > 0.8 (toxic)

NTP (U.S. National Toxicology Program) < 0.3 (noncarcinogen); > 0.8 (carcinogen)