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. 2024 Jan 6;147(1):11. doi: 10.1007/s00401-023-02662-1

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — Outcome of patients with IDH-mutant astrocytoma stratified according to CNS WHO grade and CDKN2A copy number status. (a, b) PFS (a) and OS (b) of the entire cohort of patients with IDH-mutant astrocytomas stratified by CNS WHO grade 2, 3 or 4. (c–f) PFS (c, e) and OS (d, f) of the entire cohort of patients with IDH-mutant astrocytoma (c, d) or IDH-mutant astrocytoma of CNS WHO grade 4 only (e, f)