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. 2024 Jan 6;23:12. doi: 10.1186/s12933-023-02103-z

Table 4.

Multivariate logistic regression analyses for the associations between lipid parameters with prediabetes

Model 1 Model 2 Model 3
OR (95%CI) P value OR (95%CI) P value OR (95%CI) P value
TC 1.109 (1.085,1.133)  < 0.001 1.046 (1.023,1.070)  < 0.001 1.016 (0.993,1.040) 0.164
TG 1.187 (1.166,1.207)  < 0.001 1.090 (1.070,1.110)  < 0.001 1.062 (1.042,1.082)  < 0.001
HDL-C 0.735 (0.687,0.787)  < 0.001 0.909 (0.848,0.975) 0.007 0.892 (0.831,0.958) 0.002
LDL-C 1.065 (1.035,1.096)  < 0.001 0.996 (0.967,1.026) 0.793 0.953 (0.925,0.982) 0.002
LCI 1.008 (1.007,1.009)  < 0.001 1.003 (1.002,1.004)  < 0.001 1.002 (1.001,1.003)  < 0.001
AIP 2.214 (2.065,2.374)  < 0.001 1.462 (1.356,1.577)  < 0.001 1.326 (1.227,1.433)  < 0.001
Non-HDL- C 1.154 (1.128,1.179)  < 0.001 1.061 (1.037,1.086)  < 0.001 1.031 (1.006,1.055) 0.013
AC 1.126 (1.105,1.147)  < 0.001 1.039 (1.019,1.060)  < 0.001 1.027 (1.006,1.048) 0.010
CRI-I 1.126 (1.105,1.147)  < 0.001 1.039 (1.019,1.060)  < 0.001 1.027 (1.006,1.048) 0.010
CRI-II 1.113 (1.084,1.143)  < 0.001 1.007 (0.979,1.036) 0.629 0.984 (0.956,1.013) 0.274
RC 1.498 (1.435,1.563)  < 0.001 1.271 (1.215,1.329)  < 0.001 1.257 (1.201,1.315)  < 0.001
RC/HDL-C ratio 1.397 (1.340,1.457)  < 0.001 1.188 (1.138,1.241)  < 0.001 1.186 (1.134,1.239)  < 0.001

Model 1: adjusted for age and gender at baseline

Model 2: further adjusted for family history of diabetes, BMI, SBP, and DBP based on model 1

Model 3: further adjusted for FPG, ALT, AST, Scr, and BUN based on model 2

TC total cholesterol, TG triglyceride, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, LCI lipoprotein combine index, AIP atherogenic index of plasma, AC atherogenic coefficient, CRI-I Castelli’s index-I, CRI-II Castelli’s index-II, RC remnant cholesterol, OR odds ratio, CI confidence interval