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. Author manuscript; available in PMC: 2024 Jan 7.
Published in final edited form as: J Alzheimers Dis. 2023;95(3):1147–1161. doi: 10.3233/JAD-230117

Table 1.

Characteristics of WIHS participants by HIV status

All (N=446) HIV+ (N=302) HIV− (N=144) P-value
Age, years, mean (SD) 53.1 (8.3) 53.2 (7.8) 52.8 (9.3) 0.59
Race/ethnicity, % 0.30
 Non-Hispanic black 323 (72.4) 214 (70.9) 109 (75.7)
 Hispanic 92 (20.6) 62 (20.5) 30 (20.8)
 Non-Hispanic white 19 (4.3) 16 (5.3) 3 (2.1)
 Other 12 (2.7) 10 (3.3) 2 (1.4)
Education attainment, % 0.84
 Below high school 180 (40.4) 124 (41.1) 56 (39.2)
 High school 141 (31.7) 93 (30.8) 48 (33.6)
 Above high school 124 (27.9) 85 (28.1) 39 (27.3)
Years of education 11.6 (3.0) 11.7 (3.1) 11.5 (3.0) 0.56
WRAT-3 reading subtest, mean (SD) 87.8 (18.6) 88.0 (19.1) 87.5 (17.8) 0.81
Annual income ≤$12000, % 235 (52.7) 154 (51.0) 81 (56.2) 0.35
Recreational drug use, % 105 (23.5) 66 (21.9) 39 (27.1) 0.27
 Marijuana use, % 90 (20.2) 56 (18.5) 34 (23.6) 0.26
Cigarette use, % 0.10
 Current smoker 181 (40.6) 74 (24.5) 24 (16.7)
 Former smoker 167 (37.4) 114 (37.7) 67 (46.5)
 Never smoker 98 (22.0) 114 (37.7) 53 (36.8)
Alcohol use>7 drinks/week, % 30 (6.7) 18 (6.0) 12 (8.3) 0.46
Antibiotic use, % 23 (5.2) 15 (5.0) 8 (5.6) 0.97
Hepatitis C virus antibody, % 97 (21.8) 70 (23.3) 27 (18.8) 0.34
Among HIV seropositive
 CD4 count 670 (492-923)
 HIV-1 Viral load≤20 copies/ml, % 224 (74.2)
 ART use, % 277 (91.7)
Site 0.45
 Bronx 185 (41.5) 121 (40.1) 64 (44.4)
 Brooklyn 132 (29.6) 95 (31.5) 37 (25.7)
 Chicago 129 (28.9) 86 (28.5) 43 (29.9)
Cognitive impairment 122 (27.4) 89 (29.5) 33 (22.9) 0.18
Impairment in domains
 Learning 74 (16.6) 55 (18.2) 19 (13.2) 0.23
 Memory 73 (16.4) 47 (15.6) 26 (18.1) 0.60
 Attention 62 (14.6) 45 (15.6) 17 (12.5) 0.48
 Executive function 67 (15.1) 54 (17.9) 13 (9.2) 0.02
 Motor function 62 (14.1) 44 (14.9) 18 (12.5) 0.60
 Speed 62 (13.9) 45 (14.9) 17 (11.8) 0.46
 Verbal function 60 (13.5) 46 (15.2) 14 (9.7) 0.15

Data are N (%) or mean (SD). SD: standard deviation. WRAT: Wide Range Abilities Test. HIV: human immunodeficiency virus. CD4: cluster of differentiation 4. ART: antiretroviral therapy. Recreational drug use included marijuana, crack, cocaine, heroin and injection drug use. P-values comparing characteristics by HIV status were obtained from t-test for continuous variables, Chi-squared test for categorical