Table 2.
Demographics and clinical variables of the propensity score matched cohort (N = 458) stratified by perioperative gabapentin administration.
| Gabapentin N = 229 |
No Gabapentin N = 229 |
P | |
|---|---|---|---|
| Age at surgery, years (mean, SDa) | 10.6 (4.0) | 10.4 (3.9) | 0.750 |
| Female sex | 90 (39.3) | 92 (40.2) | 0.849 |
| Race | 0.449 | ||
| Unknown | 28 (12.2) | 18 (7.9) | |
| White | 134 (58.5) | 150 (65.5) | |
| Black | 53 (23.1) | 48 (21.0) | |
| Asian | 11 (4.8) | 12 (5.2) | |
| American Indian or Alaskan Native | <10 (<4.2) | <10 (<4.2) | |
| Native Hawaiian or Pacific Islander | <10 (<4.2) | <10 (<4.2) | |
| Other | <10 (<4.2) | <10 (<4.2) | |
| Ethnicity | 0.114 | ||
| Hispanic or Latino | 69 (30.1) | 54 (23.6) | |
| Not Hispanic or Latino | 160 (69.9) | 175 (76.4) | |
| Unknown | <10 (<4.2) | <10 (<4.2) | |
| Insurance | 0.139 | ||
| Private | 87 (38.0) | 108 (47.2) | |
| Public | 125 (54.6) | 107 (46.7) | |
| Other | 17 (7.4) | 14 (6.1) | |
| Hospital Region | 0.354 | ||
| Midwest | <10 (<4.2) | <10 (<4.2) | |
| Northeast | <10 (<4.2) | 11 (4.7) | |
| South | 219 (95.6) | 217 (94.8) | |
| West | <10 (<4.2) | <10 (<4.2) | |
| Open appendectomy | 16 (7.0) | 17 (7.4) | 0.857 |
| Postoperative Outcomes | |||
| Analgesic Use | |||
| Opioidb | 118 (51.5) | 157 (68.6) | <0.001 |
| Ibuprofen | 64 (28.0) | 70 (30.6) | 0.534 |
| Ketorolac | 200 (87.3) | 202 (88.2) | 0.775 |
| Acetaminophen | 197 (86.0) | 213 (93.0) | 0.015 |
| IV acetaminophen | 11 (4.8) | 14 (6.1) | 0.537 |
| Antibiotic Utilization | |||
| Any perioperative antibiotic useb | 229 (100) | 229 (100) | – |
| Postoperative Antibiotic Use | 213 (93.0) | 217 (94.8) | 0.435 |
| Cumulative unique days of postop antibiotic use (Median, IQRc) | 4 (2.0–5.0) | 5 (3.0–6.0) | 0.923 |
| Postoperative LOS (in days)b | 4.6 (3.3)a | 5.3 (3.3)a | <0.001 |
| Postoperative Opioid Use (in days)b | 2.3 (2.3)a | 3.0 (2.5)a | <0.001 |
LOS, Length of stay.
Mean days (Standard Deviation).
Outcome variables not included in propensity score matching.
Median days (Interquartile Range).