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. Author manuscript; available in PMC: 2024 Oct 1.
Published in final edited form as: J Pediatr Surg. 2023 Mar 16;58(10):1935–1941. doi: 10.1016/j.jpedsurg.2023.03.009

Table 2.

Demographics and clinical variables of the propensity score matched cohort (N = 458) stratified by perioperative gabapentin administration.

Gabapentin
N = 229
No Gabapentin
N = 229
P
Age at surgery, years (mean, SDa) 10.6 (4.0) 10.4 (3.9) 0.750
Female sex 90 (39.3) 92 (40.2) 0.849
Race 0.449
 Unknown 28 (12.2) 18 (7.9)
  White 134 (58.5) 150 (65.5)
  Black 53 (23.1) 48 (21.0)
  Asian 11 (4.8) 12 (5.2)
  American Indian or Alaskan Native <10 (<4.2) <10 (<4.2)
  Native Hawaiian or Pacific Islander <10 (<4.2) <10 (<4.2)
  Other <10 (<4.2) <10 (<4.2)
Ethnicity 0.114
 Hispanic or Latino 69 (30.1) 54 (23.6)
  Not Hispanic or Latino 160 (69.9) 175 (76.4)
  Unknown <10 (<4.2) <10 (<4.2)
Insurance 0.139
 Private 87 (38.0) 108 (47.2)
  Public 125 (54.6) 107 (46.7)
  Other 17 (7.4) 14 (6.1)
Hospital Region 0.354
 Midwest <10 (<4.2) <10 (<4.2)
  Northeast <10 (<4.2) 11 (4.7)
  South 219 (95.6) 217 (94.8)
  West <10 (<4.2) <10 (<4.2)
Open appendectomy 16 (7.0) 17 (7.4) 0.857
Postoperative Outcomes
Analgesic Use
 Opioidb 118 (51.5) 157 (68.6) <0.001
 Ibuprofen 64 (28.0) 70 (30.6) 0.534
 Ketorolac 200 (87.3) 202 (88.2) 0.775
 Acetaminophen 197 (86.0) 213 (93.0) 0.015
 IV acetaminophen 11 (4.8) 14 (6.1) 0.537
Antibiotic Utilization
 Any perioperative antibiotic useb 229 (100) 229 (100)
 Postoperative Antibiotic Use 213 (93.0) 217 (94.8) 0.435
 Cumulative unique days of postop antibiotic use (Median, IQRc) 4 (2.0–5.0) 5 (3.0–6.0) 0.923
Postoperative LOS (in days)b 4.6 (3.3)a 5.3 (3.3)a <0.001
Postoperative Opioid Use (in days)b 2.3 (2.3)a 3.0 (2.5)a <0.001

LOS, Length of stay.

a

Mean days (Standard Deviation).

b

Outcome variables not included in propensity score matching.

c

Median days (Interquartile Range).