Table 2.
Multivariate logistic regression model analysis for the prediction of detecting csPCa by cognitive MRTB in biopsy-naive men
| Characteristic | Level | Clinical model | MRI model | Advanced model | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Coefficient | OR (95% CI) | p | Coefficient | OR (95% CI) | p | Coefficient | OR (95% CI) | p | ||
| Intercept | − 5.05 | – | < 0.001 | − 3.51 | – | 0.001 | –8.38 | – | < 0.001 | |
| Age (years) | + 10 | 0.487 | 1.63 (1.15, 2.30) | 0.006 | – | – | – | 0.83 | 2.30 (1.42, 3.72) | 0.001 |
| PSAD (ng/ml2) | + 0.05 | 1.0 | 2.72 (1.86, 3.98) | < 0.001 | – | – | – | 0.83 | 2.30 (1.44, 3.65) | < 0.001 |
| PI-RADS score | – | < 0.001 | < 0.001 | |||||||
| 3 | – | – | – | 1 | – | 1 | – | |||
| 4 | – | – | – | 1.44 | 4.24 (1.48, 12.15) | 0.007 | 1.64 | 5.17 (1.69, 15.72) | 0.004 | |
| 5 | – | – | – | 3.92 | 50.13 (12.67, 198.32) | < 0.001 | 3.94 | 51.58 (11.78, 225.86) | < 0.001 | |
| Zone of IL | TZ | – | – | 1 | 1 | – | ||||
| PZ | – | – | – | 1.87 | 6.52 (2.83, 14.99) | < 0.001 | 2.34 | 9.35 (3.56, 24.56) | < 0.001 | |
| Level of IL | – | 0.107 | 0.563 | |||||||
| Base | – | – | – | 1 | 1 | – | ||||
| Mid | – | – | – | 0.76 | 2.14 (0.76, 6.02) | 0.149 | 0.28 | 1.32 (0.42, 4.14) | 0.635 | |
| Apex | – | – | – | 1.25 | 3.48 (1.09, 11.04) | 0.035 | 0.67 | 1.95 (0.54, 7.04) | 0.307 | |
| MD of IL (cm) | – | 0.831 | – | – | – | |||||
| < 0.8 | – | – | – | 1 | – | – | – | – | ||
| 0.8–1.4 | – | – | – | 0.112 | 1.12 (0.19, 6.54) | 0.901 | – | – | – | |
| ≥ 1.5 | – | – | – | –0.19 | 0.827 (0.124, 5.50) | 0.845 | – | – | – | |
CI confidential interval, IL index lesion, MD maximum diameter, OR odds ratio, PI-RADS Prostate Imaging Reporting and Data System, PSAD prostate-specific antigen density