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Protein/phosphoprotein signaling activation clusters linkage to sensitivity/resistance
(A) One-way hierarchical clustering map of protein/phosphoprotein analyte-mean signaling levels (columns) within each RPPA signaling cluster (rows). Heatmap color scale: red/white/blue, higher/intermediate/lower levels of expression.
(B) Sankey plot illustrating relationship of trial arms (left), RPPA signaling clusters (center), and pCR (right).
