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. 2023 Dec 11;4(12):101312. doi: 10.1016/j.xcrm.2023.101312

Figure 6.

Figure 6

DRFS association within non-pCR patients by RPPA cluster

(A) Hazard ratio (HR) for DRFS for pCR by signaling cluster (box size, power; whiskers, 95% confidence interval (CI).

(B) Kaplan-Maier plots of DRFS in the non-pCR patient subset for all 11 RPPA signaling clusters (B.1). (B.2–B.4) Kaplan-Meier plots of DRFS comparing patients achieving pCR across the whole population (blue curves), to non-pCR patients (red curves) in cluster 9 (B.2), cluster 2 (B.3), and cluster 8 (B.4).

(C) Dot plot demonstrating association of individual protein/phosphoprotein analytes (columns) with DRFS in each of the 11 RPPA signaling clusters (rows) within non-pCR patients. Analytes included are limited to those with significant or nominal association in at least one RPPA signaling cluster.