Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Incidence of adverse events (AE) over time for grade ≥3 AE (A), any-grade serious AE (B), and any-grade select AE of interest (C; atrial fibrillation and major hemorrhage). A patient with multiple severity grades for a given AE was counted only once under the maximum severity. Multiple onsets of the same AE within a specific yearly interval were counted once, and the same AE term continuing across several yearly intervals was counted in each of the intervals; y: years.
