Table 5.

Reclassification and discrimination statistics for 5-year all-cause death and MACCE by hs-CRP and/or HbA1c.

Model	AUC Estimate (95%CI)		NRI		IDI
		P value	Estimate (95%CI)	P value	Estimate (95%CI)	P value
All cause death
Conventional modela	0.820 (0.788–0.853)	–	Reference	–	Reference	–
Conventional model + hs-CRP	0.823 (0.790–0.855)	0.476	0.014(-0.148–0.175)	0.867	0.006(0.002–0.011)	0.009
Conventional model + HbA1c	0.827 (0.796–0.859)	0.195	−0.045(-0.210–0.119)	0.590	0.002(-0.002–0.005)	0.335
Conventional model + hs-CRP + HbA1c	0.829 (0.798–0.860)	0.009	0.492(0.325–0.658)	<0.001	0.007(0.002–0.012)	0.011
MACCE
Conventional modela	0.667 (0.647–0.687)	–	Reference	–	Reference	–
Conventional model + hs-CRP	0.671 (0.651–0.691)	0.1365	0.064(-0.006–0.134)	0.072	0.003(0.001–0.004)	<0.001
Conventional model + HbA1c	0.672 (0.652–0.692)	0.1069	0.117(0.043–0.192)	0.002	0.004(0.002–0.006)	<0.001
Conventional model + hs-CRP + HbA1c	0.675 (0.655–0.695)	0.0233	0.160(0.086–0.234)	<0.001	0.006(0.003–0.008)	<0.001

AUC, area under the curve; NRI, net reclassification index; IDI, integrated discrimination improvement; CI, confidence interval; Hs-CRP, high –C reaction protein; HbA1c, hemoglobin, type A1C; MACCE, major adverse cardiac and cerebrovascular events.

^aThe conventional model included gender, age, body mass index, hypertension, hyperlipidemia, diabetes mellitus, chronic kidney disease, hyperuricemia, current smoker, the family history of coronary artery disease, left ventricular ejection fraction, the synergy between percutaneous coronary intervention with Taxus and cardiac surgery score, old myocardial infarction, previous percutaneous coronary intervention.