Table 1.
Effect of SA and SU Extracts (500-1000 µg/ml) on Cell Cycle Progression in DU-145 and PC-3 Cells after 48 hours
| DU-145 | PC-3 | |||||
|---|---|---|---|---|---|---|
| G0/G1 | S | G2/M | G0/G1 | S | G2/M | |
| Control | 72.69+1.25 | 11.12+2.57 | 13.92+1.28 | 83.84+4.06 | 7.00+2.65 | 15.42+2.61 |
| SA 500 µg/ml | 63.00+1.23* | 21.35+1.20* | 12.60+1.95 | 56.86+14.79* | 17.92+7.85* | 10.07+4.08* |
| SA 1000 µg/ml | 65.57+2.11* | 19.42+3.64* | 10.02+3.35 | 63.09+11.63* | 11.05+3.55* | 10.94+3.46* |
| Control | 72.69+1.25 | 11.12+2.57 | 13.92+1.28 | 83.84+4.06 | 7.00+2.65 | 15.42+2.61 |
| SU 500 µg/ml | 65.36+0.89* | 21.53+1.07* | 10.65+2.08 | 72.88+1.51* | 11.91+3.18* | 13.34+1.77 |
| SU 1000 µg/ml | 64.58+0.62* | 22.81+1.70* | 10.21+2.78 | 68.67+3.91** | 9.71+1.10* | 14.80+0.96 |
Results are expressed as a percentage of total cells. Significant differences between untreated cells (Control) and cells treated with grape extracts were compared (* p < 0.05; ** p < 0.01;). Abbreviations: SA, Sweet sapphire; SU, Sweet surprise.