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. Author manuscript; available in PMC: 2024 Jan 8.
Published in final edited form as: Pediatr Pulmonol. 2021 Jul 28;56(10):3183–3188. doi: 10.1002/ppul.25592

Table 3.

Demographic characteristics at 6, 12, 18, 24 and 30 months of age, by groups.

Survey at 6 months Survey at 12 months Survey at 18 months Survey at 24 months Survey at 30 months
Positive API n= 44 Negative API n=262 Positive API n= 44 Negative API n=244 Positive API n= 43 Negative API n=239 Positive API n= 42 Negative API n=217 Positive API n= 37 Negative API n=169
Age start day-care (mo) 0.40 ± 1.5 0.33 ± 1.3 2.29 ± 3.8* 0.97 ± 2.8 3.73± 5.2 2.53 ± 5.7 3.73± 5.2 2.53 ± 5.7 4.62 ± 7.0 6.04 ± 10.05
GERD 21.6 10.2 15.0 * 4.9 2.3 0.8 2.3 0.8 0.0 0.5
AOM 5.4 1.6 12.5 6.6 20.9 * 7.6 7.1 8.4 10.8 6.7
Bronchiolitis 86.5 *** 24.7 87.2 *** 38.6 81.4 *** 34.3 95.2 *** 48.4 97.3 *** 42.6
Croup 16.2 ** 2.9 20.0 10.0 27.9 ** 10.5 27.9 ** 10.5 16.2 * 5.1
Pneumonia 13.9 ** 2.9 25.0 * 9.9 18.6 8.9 47.6 *** 18.2 54.1 *** 16.5
Antibiotics use 43.2 *** 12.3 65.0 *** 36.0 69.8 ** 43.9 54.8 41.4 40.5 41.5
AB respiratory illness 8.3 4.1 15.0 17.4 67.4 ** 43.6 54.8 40.2 37.8 41.0
Acetaminophen use 94.6 91.8 87.5 90.2 86.0 82.0 86.0 82.0 59.5 63.3
Pets at home 45.9 ** 23.0 17.5 24.8 25.6 24.5 26.2 26.9 24.3 30.4
Never smoking inside 94.4 94.7 95.0 95.9 95.3 96.6 95.2 98.1 94.6 96.4
Never smoking outside 37.8 42.6 35.0 43.0 34.9 42.2 40.5 48.1 43.2 40.0
Cough after crying, laughing, or agitation 32.4 *** 4.9 45.0 *** 8.3 46.3 *** 9.1 41.5 *** 7.9 54.1 *** 9.2
MD asthma diagnosis 2.7 0.8 20.0 *** 3.3 40.5 *** 7.5 36.6 *** 6.5 43.2 *** 7.2
Ever OCS use 83.8 *** 21.4 82.5 *** 34.9 70.7 *** 30.9 70.7 *** 29.8 86.5 *** 28.2
Ever ICS use 10.8 ** 1.2 43.6 *** 7.1 45.2 *** 8.7 39.0 *** 9.3 37.8 *** 9.2
ED for WE 56.8 *** 16.5 70.0 *** 25.3 64.3 *** 23.4 43.9 *** 13.9 43.2 *** 9.2
Hospitalization for WE 21.6 ** 7.0 17.5 * 5.8 14.3 ** 2.2 7.3 * 0.9 10.8 * 1.5

Number expressed as percent (%) for categorical variables or mean ± SD for continuous variables.

AB= antibiotics; AOM= acute otitis media; ED= emergency department; GERD= gastroesophageal reflex; ICS= inhaled corticosteroids; OCS= oral corticosteroids; WE= wheezing episodes.

p < 0.05*, p≤0.01**, p≤0.001***, for trend test ANOVA (continue variables) or exact Fisher (categorical variables) comparing with negative API.