Table 2.
Clinical and demographic characteristics of the Bio-FINDER-2 cohort
| CU (N = 149) | MCI (N = 47) | AD (N = 63) | OND (N = 95) | Overall (N = 354) | |
|---|---|---|---|---|---|
| Sex | |||||
| Female, n (%) | 78 (52.3%) | 20 (42.6%) | 30 (47.6%) | 61 (64.2%) | 189 (53.4%) |
| Male, n (%) | 71 (47.7%) | 27 (57.4%) | 33 (52.4%) | 34 (35.8%) | 165 (46.6%) |
| Age, years | |||||
| Mean (SD) | 64.7 (13.5) | 73.1 (7.52) | 74.4 (6.70) | 70.5 (9.36) | 69.1 (11.5) |
| Education, years | |||||
| Mean (SD) | 12.5 (3.48) | 12.5 (3.73) | 11.6 (4.06) | 12.2 (3.46) | 12.3 (3.61) |
| Missing | 0 (0%) | 1 (2.1%) | 0 (0%) | 0 (0%) | 1 (0.3%) |
| MMSE | |||||
| Mean (SD) | 29.0 (1.13) | 26.6 (1.92) | 19.6 (4.50) | 25.5 (4.32) | 26.1 (4.56) |
| APOEε4 carriers | |||||
| Noncarriers, n (%) | 79 (53.0%) | 14 (29.8%) | 20 (31.7%) | 61 (64.2%) | 174 (49.2%) |
| Carriers, n (%) | 70 (47.0%) | 32 (68.1%) | 43 (68.3%) | 34 (35.8%) | 179 (50.6%) |
| Missing | 0 (0%) | 1 (2.1%) | 0 (0%) | 0 (0%) | 1 (0.3%) |
| Neocortical (18F)Flutametamol SUVR | |||||
| Mean (SD) | 1.01 (0.21) | 1.50 (0.29) | 1.66 (0.2) | 0.958 (0.08) | 1.11 (0.30) |
| Missing | 11 (7.4%) | 8 (17.0%) | 59 (93.7%) | 67 (70.5%) | 145 (41.0%) |