Table 2.
Prognostic factors for PFS selected by Cox’s univariate and multivariate analysis
| Exp(B) | 95% CI | Cox’s test | Exp(B) | 95% CI | Cox’s test | |
|---|---|---|---|---|---|---|
| P value | P value | |||||
| Age (≧ 70 years) | 1.393 | 0.804–2.413 | 0.237 | |||
| BMI (<18.5) | 1.62 | 0.731–3.591 | 0.235 | |||
| Stage (≧stage IV) | 1.994 | 1.166–3.411 | 0.012* | 1.935 | 1.128–3.317 | 0.016* |
| Histology (HGSC) | 0.691 | 0.369–1.293 | 0.248 | |||
| HRP | 2.006 | 0.940–4.280 | 0.072 | |||
| gBRCA wild type (include VUS) | 4.654 | 2.152–10.065 | <0.001* | 4.583 | 2.116–9.923 | <0.001* |
| PDS absent | 1.352 | 0.680–2.689 | 0.39 | |||
| Interval debulking surgery (≧R1) | 1.536 | 0.878–2.688 | 0.133 | |||
| Response to the last platinum therapy (PR) | 1.552 | 0.901–2.673 | 0.114 |
BMI: body mass index, HGSC: high-grade serous carcinoma, HRP: homologous recombination proficient, PR: partial response, *P < 0.05