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(A) shows composition of the TME: TME is a complex system, which is divided into cellular and non-cellular components. Cellular components include ECs, CAFs, TAMs, DCs, T cells, Regulatory T cells, B-cells, NK cells, MDSCs etc. Non cellular components include ECM and extracellular cytokines etc. (B) shows the composition of nano carriers modified by cell membrane. At present, cell membranes are mainly studied, including Erythrocyte, Tumor cell, Macrophage, NK cell, Neutrophils etc.
