TABLE 2.
CRPC | mHSPC | |||||
---|---|---|---|---|---|---|
White (N = 241) |
Black (N = 65) |
P-value | White (N = 463) |
Black (N = 110) |
P-value | |
EORTC QLQ-C30 Pain Scale (0–100)a Minimally important difference: 5 points |
||||||
Mean (SD) | 18.4 (23.1) | 26.2 (28.1) | 0.05 | 19.1 (25.0) | 26.7 (30.0) | 0.03 |
Missing | n = 33 | n = 4 | n = 67 | n = 19 | ||
Q1: How often have you had pain in the past week? | ||||||
1 – Not at all | 108 (51%) | 23 (38%) | 0.13 | 200 (51%) | 38 (41%) | 0.09 |
2 – A little | 77 (37%) | 25 (41%) | 138 (35%) | 33 (36%) | ||
3 – Quite a bit | 18 (9%) | 8 (13%) | 42 (11%) | 12 (13%) | ||
4 – Very much | 7 (3%) | 5 (8%) | 16 (4%) | 9 (10%) | ||
Missing | n = 31 | n = 4 | n = 67 | n = 18 | ||
Q2: How often did pain interfere with your daily activities in the past week? | ||||||
1 – Not at all | 132 (63%) | 34 (56%) | 0.26 | 265 (67%) | 53 (58%) | 0.11 |
2 – A little | 58 (28%) | 17 (28%) | 96 (24%) | 22 (24%) | ||
3 – Quite a bit | 15 (7%) | 7 (11%) | 20 (5%) | 8 (9%) | ||
4 – Very much | 3 (1%) | 3 (5%) | 16 (4%) | 8 (9%) | ||
Missing | n = 33 | n = 4 | n = 66 | n = 19 | ||
Brief Pain Inventory (BPI) Minimally important difference: 1.3–1.6 points |
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Rate your average pain (1–10) | ||||||
Mean (SD) | 2.2 (1.6) | 3.1 (2.2) | 0.01 | 2.2 (1.6) | 3.2 (2.4) | <0.001 |
Missing | n = 42 | n = 10 | n = 73 | n = 19 | ||
Rate your pain at its worst in the last 24 hours (1–10) | ||||||
4 or greater | 48 (24%) | 18 (33%) | 0.27 | 85 (22%) | 37 (41%) | <0.001 |
Less than 4 | 151 (76%) | 37 (67%) | 305 (78%) | 54 (59%) | ||
Missing | n = 42 | n = 10 | n = 73 | n = 19 | ||
FACT-FPSI Minimally important difference: Not established |
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How often have you had bone pain in the past week? | ||||||
0 – Not at all | 120 (60%) | 31 (55%) | 0.90 | 234 (61%) | 49 (55%) | 0.27 |
1 – A little bit | 42 (21%) | 14 (25%) | 86 (22%) | 21 (24%) | ||
2 – Somewhat | 21 (11%) | 6 (11%) | 27 (7%) | 5 (6%) | ||
3 – Quite a bit | 10 (5%) | 4 (7%) | 31 (8%) | 9 (10%) | ||
4 – Very much | 6 (3%) | 1 (2%) | 7 (2%) | 5 (6%) | ||
Missing | n = 42 | n = 9 | n = 78 | n = 21 |
Abbreviations: CRPC, castration-resistant prostate cancer; mHSPC, metastatic hormone-sensitive prostate cancer.
aThe EORTC pain scale score is created through a linear transformation of Q1 and Q2 below.