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. 2024 Jan 8;4(1):55–64. doi: 10.1158/2767-9764.CRC-23-0446

TABLE 2.

Average pain at study enrollment by disease state at enrollment and self-reported race (N = 4 pain scales)

CRPC mHSPC
White
(N = 241)
Black
(N = 65)
P-value White
(N = 463)
Black
(N = 110)
P-value
EORTC QLQ-C30 Pain Scale (0–100)a
Minimally important difference: 5 points
  Mean (SD) 18.4 (23.1) 26.2 (28.1) 0.05 19.1 (25.0) 26.7 (30.0) 0.03
  Missing n = 33 n = 4 n = 67 n = 19
 Q1: How often have you had pain in the past week?
  1 – Not at all 108 (51%) 23 (38%) 0.13 200 (51%) 38 (41%) 0.09
  2 – A little 77 (37%) 25 (41%) 138 (35%) 33 (36%)
  3 – Quite a bit 18 (9%) 8 (13%) 42 (11%) 12 (13%)
  4 – Very much 7 (3%) 5 (8%) 16 (4%) 9 (10%)
  Missing n = 31 n = 4 n = 67 n = 18
 Q2: How often did pain interfere with your daily activities in the past week?
  1 – Not at all 132 (63%) 34 (56%) 0.26 265 (67%) 53 (58%) 0.11
  2 – A little 58 (28%) 17 (28%) 96 (24%) 22 (24%)
  3 – Quite a bit 15 (7%) 7 (11%) 20 (5%) 8 (9%)
  4 – Very much 3 (1%) 3 (5%) 16 (4%) 8 (9%)
  Missing n = 33 n = 4 n = 66 n = 19
Brief Pain Inventory (BPI)
Minimally important difference: 1.3–1.6 points
 Rate your average pain (1–10)
  Mean (SD) 2.2 (1.6) 3.1 (2.2) 0.01 2.2 (1.6) 3.2 (2.4) <0.001
  Missing n = 42 n = 10 n = 73 n = 19
 Rate your pain at its worst in the last 24 hours (1–10)
  4 or greater 48 (24%) 18 (33%) 0.27 85 (22%) 37 (41%) <0.001
  Less than 4 151 (76%) 37 (67%) 305 (78%) 54 (59%)
  Missing n = 42 n = 10 n = 73 n = 19
FACT-FPSI
Minimally important difference: Not established
 How often have you had bone pain in the past week?
  0 – Not at all 120 (60%) 31 (55%) 0.90 234 (61%) 49 (55%) 0.27
  1 – A little bit 42 (21%) 14 (25%) 86 (22%) 21 (24%)
  2 – Somewhat 21 (11%) 6 (11%) 27 (7%) 5 (6%)
  3 – Quite a bit 10 (5%) 4 (7%) 31 (8%) 9 (10%)
  4 – Very much 6 (3%) 1 (2%) 7 (2%) 5 (6%)
  Missing n = 42 n = 9 n = 78 n = 21

Abbreviations: CRPC, castration-resistant prostate cancer; mHSPC, metastatic hormone-sensitive prostate cancer.

aThe EORTC pain scale score is created through a linear transformation of Q1 and Q2 below.