Table 3.

Pearson correlations (R) between dry eye (DE) disease and sleep metrics

	PSQI total	PSQI 1 subjective quality	PSQI 2 latency	PSQI 3 duration	PSQI 4 efficiency	PSQI 5 disturbance	PSQI 6 medication	PSQI 7 daytime dysfunction
Ocular symptoms
DEQ-5	0.41*	0.43*	0.27*	0.27*	0.23*	0.44*	0.05	0.40*
OSDI	0.43*	0.47*	0.23*	0.26*	0.14	0.49*	0.13	0.37*
NRS (right now)	0.30*	0.34*	0.13	0.15	0.06	0.36*	0.12	0.30*
NRS (average of 1 week)	0.32*	0.36*	0.12	0.20*	0.14	0.41*	0.07	0.31*
NRS (worst in 1 week)	0.31*	0.34*	0.11	0.18*	0.10	0.45*	0.06	0.30*
NPSI-E	0.35*	0.37*	0.10	0.22*	0.03	0.44*	0.16	0.44*
CISS	0.48*	0.48*	0.21*	0.29*	0.13	0.51*	0.19*	0.56*
Ocular surface exam†
Eyelid laxity upper	0.04	0.04	0.02	−0.09	0.06	−0.02	0.09	0.00
Eyelid laxity lower	0.04	0.05	0.03	−0.01	0.03	0.00	0.12	−0.04
Ocular surface inflammation	0.20*	0.29*	0.16	0.06	0.11	0.14	0.00	0.20*
Corneal sensation	0.19*	0.05	0.14	0.05	0.09	0.19	0.07	0.14
Anterior blepharitis	0.08	0.03	0.05	0.09	0.11	0.03	0.00	−0.01
Conjunctivochalasis	0.22*	0.14	0.07	0.18*	0.13	0.11	0.11	0.22*
Tear break-up time	−0.12	−0.03	−0.14	−0.07	−0.12	0.02	−0.12	0.08
Papillary conjunctivitis	−0.01	−0.04	−0.05	−0.09	0.01	0.01	0.07	−0.14
Corneal stain	0.09	0.07	−0.04	0.11	0.13	0.08	−0.01	0.00
Schirmer score	0.05	0.02	0.13	0.06	0.05	−0.04	−0.13	0.15
Vascularity	−0.05	−0.04	−0.12	−0.09	−0.01	0.03	0.06	−0.07
Meibum quality	0.17	0.29*	0.07	0.22*	0.03	0.00	0.09	0.07

*Correlation is significant at the 0.05 level (two tailed).

†Measurement from more severely affected eye.

‡Green = positive correlation, red = negative correlation.

CISS, Convergence Insufficiency Symptoms Survey; DEQ-5, 5-Item Dry Eye Questionnaire; NPSI-E, Neuropathic Pain Symptom Inventory modified for the Eye; NRS, Numerical Rating Scale; OSDI, Ocular Surface Disease Index; PSQI, Pittsburgh Sleep Quality Index.