Table 2.

Pre and postintervention screening practices

	Preintervention	Postintervention	Combined	P Value
No. of subjects	229	113	342	—
Patients screened for AATD (any screen)	21 (9.2%)	23 (20.4%)	44 (12.8%)	0.004
Screen type*
AAT concentration	5 (2.2%)	14 (12.4%)	19 (5.6%)	<0.001
Average concentration, mg/dl (range)	130.2 (75.0–115.0)	140.4(52.0–184.0)	137.7 (52.0–184.0)	0.354
>80 mg/dl	4	13	17
<80 mg/dl	1	1	2
Phenotype/genotype	17 (7.4%)	11 (9.7%)	28 (8.2%)	0.046
M/M	11	5	16
M/S	3	1	4
M/Z	1	2	3
S/Z	0	1	1
Z/Z	2	2	4
Location of screen*
At UAB	18 (7.9%)	17 (15.0%)	35 (10.2%)	0.039
Outside UAB†	3 (1.3%)	6 (5.3%)	9 (2.6%)	0.020

Definition of abbreviations: AAT = alpha-1 antitrypsin; AATD = alpha-1 antitrypsin deficiency; UAB = University of Alabama at Birmingham.

^*Patients could have multiple types of screens performed.

^† Reported by our documentation/outside record gathering.