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. 2023 Dec 19;14:1303426. doi: 10.3389/fendo.2023.1303426

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Copyright © 2023 Qin, Cao, Ding, Zeng, Deng and Luo

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Construction and Validation of Ferroptosis Score. (A) Using Cytoscape and CytoHubba to identify 8 modular genes to construct ferroptosis score and visualize molecular interaction networks. (B–D) Differences in ferroptosis score between two ferroptosis subgroups in GSE40481, GSE109345 and GSE162694. (E) Correlation between ferroptosis score genes. (F–H) The receiver operating characteristic (ROC) curve for differentiating ferroptosis subgroups by ferroptosis score in GSE40481 (AUC=0.937), GSE109345 (AUC=0.859) and GSE162694 (AUC=0.911). (I) Bubble diagram of the relationship between 8 score genes and immune cells.