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. 2023 Dec 18;14:1287350. doi: 10.3389/fmicb.2023.1287350

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Copyright © 2023 Vernocchi, Marangelo, Guerrera, Del Chierico, Guarrasi, Gardini, Conte, Paci, Ianiro, Gasbarrini, Vicari and Putignani.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Differential abundances of VOCs between ASDs with clinical symptoms and ASD with risk of clinical symptoms, reported as CBCL-based score, vs ASD with no clinical symptoms. (A) CBCL-INT and CBCL-EXT, both related to ASDs with presence of clinical symptoms vs ASDs with no clinical symptoms. (B) CBCL-INT risk subgroup vs ASDs with no clinical symptoms. (C) CBCL-EXT risk subgroup vs ASDs with no clinical symptoms. Colors: (A) Blue, CBCL-INT and CBCL-EXT including ASDs with clinical symptoms; green, ASDs with no clinical symptoms; (B) and (C) red, CBCL-INT and CBCL-EXT including with ASDs with risk of clinical symptoms; green, ASDs with no clinical symptoms. p ≤ 0.05 based on Mann–Whitney test.