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. 2023 Dec 19;11:1257629. doi: 10.3389/fpubh.2023.1257629

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Copyright © 2023 Tyler, Podaras, Richardson, Roeder, Hammond, Hamilton, Blum, Gold, Baron and Thanos.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Quantitative autoradiography of [³H]SCH 23390 (D1R-like) binding levels within the nucleus accumbens shell (Nac Shell), nucleus accumbens core (Nac Core), ventromedial caudate putamen (VL CPU), ventrolateral caudate putamen (VL CPU), dorsolateral caudate putamen (DL CPU), dorsomedial caudate putamen (DM CPU), dorsal caudate putamen (D CPU), ventral caudate putamen (V CPU), olfactory tubercle (OT), and substantia nigra (SNR) across exercise treatment groups. Measurements of the following regions were carried out at the bregma coordinates taken from the Paxinos & Watson rat brain atlas. Values are expressed as total [³H]SCH 23390 binding means ± S.E.M. for D1R receptors. No significant group differences were observed (p > 0.05). Each bar represents the group mean for dopamine D1 receptor binding.