Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Summary of meta-analysis findings in the overall primary prevention population
| Outcome | Certainty of evidence | Effect estimate |
|
|---|---|---|---|
| RR (95% CI) | Absolute change, per 1000 | ||
| MACE | High | 0.90 (0.86–0.94) | 4 fewer (from 6 to 2 fewer) |
| ICH | High | 1.33 (1.13–1.56) | 1 more (from 0 to 2 more) |
| ECMB | High | 1.67 (1.36–2.06) | 5 more (from 3 to 8 more) |
CI, confidence interval; ECMB, extracranial major bleeding; ICH, intracranial hemorrhage; MACE, major adverse cardiovascular events; RR, risk ratio (relative risk).
