Table 3.
Characteristics of the Included Studies
| Trials | Type of Study | Sample Size, n | Age, y | Sex, M/F | Intervention in Experimental Group | Intervention in Control Group | Outcome Measures | Major Findings |
|---|---|---|---|---|---|---|---|---|
| Gehlot et al28 | RCT | 20 | Not reported | Not reported | Group A: Sciatic nerve mobilization+ Conventional PT Duration: 5 d/wk, 4 wk |
Group B: Conventional PT Duration: 5 d/wk, 4 wk |
Weight bearing asymmetry ROM (flexion and extension) |
↑ in ROM and improvement in weight bearing asymmetry |
| Kumar et al29 | Pilot RCT | 34 | 53.86 ± 9.85 | 26/18 | Experimental limb: Nerve slider technique + nerve massage | Control limb: Sham intervention consisted of midrange rhythmic passive joint movements performed by a physiotherapist at .5Hz, each movement for 5 repetitions, at ankle, subtalar, midfoot, forefoot and toes | VPT, HPT, and CPT | Greater ↓ in VPT, HPT, and CPT on the experimental limb |
| Ali et al30 | Case series | 40 | 51.22 ± 6.71 | 8/31 | Nerve sliders for radial, ulnar and median nerves Duration: 10 s with 2 s rest and 10 repetitions |
No control | DN4 | ↓ in DN4 |
| Boyd et al31 | Cross-sectional study | 43 | 56.3 ± 11.1 | 22/21 | Straight leg raise neurodynamic tests were performed with ankle plantar flexion (PF/SLR) and dorsiflexion (DF/SLR) | No control | MDNS, MNSIq, VPT, EMG, SLR | Strong correlations between MDNS and MNSIc (0.82, P < .0005); MDNS and VPT-AVG (0.76, P < .0005). ↑Hip ROM from P1 to P2 in SLR for both DF/SLR and PF/SLR (P < .0005). In start position, 2 times ↑MVC (5.3 ± 4.1% MVC to 9.7 ± 8.9% MVC). |
| Doshi et al32 | Pre-post study | 20 | 50-60 | 9/11 | Tibial nerve mobilization | No control | SNCV | ↑ in SNCV |
| Manu et al33 | Case study | 1 | 63 | 1/0 | Tibial nerve mobilization | No control | FA, ADC, Pain, QOL, ROM | ↑ FA, ↓ADC, ↑QOL, ↑ ROM, ↓Pain |
ADC, apparent diffusion coefficient; AVG, average; CPT, cooling perception thresholds; DF, dorsiflexion; DN4, douleur neuropathic; EMG, electromyography; FA, fractional anisotropy; HPT, heat perception thresholds; MDNS, Michigan Diabetic Neuropathy Score; MNSIc, Michigan Neuropathy Screening Instrument clinical examination; MNSIq, Michigan Neuropathy Screening Instrument questionnaire; M/F, male/female; MVC, maximum voluntary contraction; PF, platarflexion; PT, physical therapy; QOL, quality of life; RCT, randomized controlled trials; ROM, range of motion; SLR, straight leg raise; SNCV, sensory nerve conduction velocity; VPT, vibration perception threshold.