Table 1.
Baseline patient characteristics
| Overall (N = 925) | LLL (n = 655) | SDL (n = 270) | P value | |
|---|---|---|---|---|
| Age (y) | 75 ± 13 | 74 ± 14 | 76 ± 10 | .013 |
| Hypertension | 685 (74) | 480 (73) | 205 (76) | .107 |
| Diabetes | 332 (36) | 239 (37) | 93 (34) | .667 |
| Chronic kidney disease | 339 (37) | 247 (38) | 92 (34) | .495 |
| Structural heart disease | 481 (52) | 372 (57) | 109 (40) | <.001 |
| NYHA functional class | .005 | |||
| I | 350 (38) | 233 (36) | 117 (43) | |
| II | 433 (47) | 311 (47) | 122 (45) | |
| III | 124 (13) | 104 (16) | 20 (7) | |
| IV | 2 (0.2) | 1 (0.2) | 1 (0.4) | |
| Baseline LVEF (%) | 54 ± 15 | 53 ± 15 | 57 ± 12 | <.001 |
| LVEF ≤50% | 259 (28) | 210 (32) | 49 (18) | <.001 |
| Ischemic heart disease | 194 (21) | 158 (24) | 36 (13) | .003 |
| Valvular heart disease | 203 (22) | 141 (22) | 62 (23) | .662 |
| Interventricular septum width (mm) | 12.4 ± 5.1 | 12.2 ± 2.5 | 12.9 ± 8.6 | .042 |
| LA diameter (mm) | 41 ± 8 | 41 ± 8 | 41 ± 7 | .372 |
| Pacing indication | <.001 | |||
| SND | 171 (18) | 97 (15) | 74 (27) | |
| AVB | 554 (60) | 382 (58) | 172 (64) | |
| CRT | 165 (18) | 145 (22) | 20 (7) | |
| Ablate and pace | 35 (4) | 31 (5) | 4 (2) | |
| Baseline QRS duration (ms) | 138 ± 37 | 141 ± 37 | 132 ± 36 | .002 |
| Baseline QRS morphology | <.001 | |||
| Normal | 301 (33) | 198 (30) | 103 (38) | |
| RBBB | 239 (26) | 166 (25) | 73 (27) | |
| LBBB | 201 (22) | 155 (24) | 46 (17) | |
| IVCD | 41 (5) | 25 (4) | 16 (6) | |
| Paced | 128 (14) | 106 (16) | 22 (8) |
Values are given as mean ± SD or n (%) unless other indicated.
AVB = atrioventricular block; CRT = cardiac resynchronization therapy; IVCD = intraventricular conduction disturbance; LA = left atrium; LBBB = left bundle branch block; LLL = lumenless lead; LVEF = left ventricular ejection fraction; NYHA = New York Heart Association; RBBB = right bundle branch block; SDL = stylet-driven lead; SND = sinus node disease.