Table E1.
Baseline characteristics for patients undergoing SMVr stratified by follow-up MR ≤1.5 versus ≥2.0 within 1 year of procedure
| Overall | MR ≤1.5, n = 368 | MR ≥2.0, n = 25 | P value | |
|---|---|---|---|---|
| Age, y | 63.8 ± 13.3 | 63.7 ± 13.3 | 65.7 ± 13.4 | .46 |
| Sex (male) | 62.3% | 63.6% | 44.0% | .05 |
| Hypertension | 75.3% | 75.0% | 80.0% | .81 |
| Hyperlipidemia | 68.7% | 68.5% | 72.0% | .71 |
| Diabetes | 25.7% | 25.3% | 32.0% | .46 |
| Depression history | 27.0% | 28.0% | 12.0% | .10 |
| Previous myocardial infarction | 14.2% | 13.9% | 20.0% | .38 |
| Coronary artery disease | 60.6% | 60.6% | 60.0% | .95 |
| Heart failure | 61.6% | 60.9% | 72.0% | .27 |
| Previous percutaneous coronary intervention | 7.9% | 8.2% | 4.0% | .71 |
| Previous coronary artery bypass graft | 18.1% | 18.5% | 12.0% | .59 |
| Previous stroke | 7.9% | 8.2% | 4.0% | .71 |
| Previous transient ischemic attack | 7.1% | 7.3% | 4.0% | 1.00 |
| Atrial fibrillation history | 53.7% | 53.0% | 64.0% | .29 |
| Atrial flutter history | 20.4% | 19.8% | 28.0% | .33 |
| Implantable cardioverter defibrillator | 2.8% | 2.4% | 8.0% | .15 |
| Pacemaker | 5.9% | 5.7% | 8.0% | .65 |
| Body mass index, kg/m2 | ||||
| Mean ± SD | 27.4 ± 5.0 | 27.4 ± 5.0 | 27.6 ± 4.3 | .96 |
| Category | .86 | |||
| <25.0 | 31.8% | 32.3% | 24.0% | |
| 25-29.9 | 41.7% | 41.3% | 48.0% | |
| ≥30 | 26.5% | 26.4% | 28.0% | |
| STS predicted risk of mortality score (%), n = 222 | 1.8 ± 3.2 | 1.8 ± 3.2 (n = 211) | 2.3 ± 2.5 (n = 11) | .62 |
| LVEF closest before mitral procedure | ||||
| Number of patients | 378 | 353 | 25 | |
| Days, median (range) | 28 (1, 2272) | 28 (1, 2272) | 24 (1, 1734) | .86 |
| EF | 56.9 ± 11.2 | 57.0 ± 11.2 | 55.8 ± 10.9 | .62 |
| LVIDd closest prior to mitral procedure | ||||
| Number of patients | 356 | 334 | 22 | |
| Days, median (range) | 32 (1, 2952) | 32 (1, 2952) | 35 (1, 624) | .24 |
| LVIDd | 5.1 ± 0.8 | 5.1 ± 0.8 | 5.2 ± 0.7 | .56 |
| Number of patients | 354 | 331 | 23 | |
| Days, median (range) | 33 (1, 2853) | 33 (1, 2853) | 39 (1, 624) | .27 |
| LA size closest before mitral procedure | ||||
| Number of patients | 262 | 242 | 20 | |
| Days, median (range) | 42 (1, 4767) | 41.5 (1, 4767) | 120.5 (1, 2714) | .06 |
| Categories | .20 | |||
| 0 | 14.2% | 13.7% | 20.0% | |
| 1.0 | 22.6% | 23.2% | 15.0% | |
| 1.5 | 19.2% | 18.7% | 25.0% | |
| 2.0 | 15.3% | 14.1% | 30.0% | |
| 2.5 | 8.0% | 8.3% | 5.0% | |
| 3.0 | 20.7% | 22.0% | 5.0% | |
| Right ventricular size closest before mitral procedure | ||||
| Number of patients | 352 | 330 | 22 | |
| Categories | .15 | |||
| Normal to mild | 87.8% | 88.5% | 77.3% | |
| Moderate | 10.2% | 9.4% | 22.7% | |
| Severe | 2.0% | 2.1% | 0% | |
| Right ventricular function closest before mitral procedure | ||||
| Number of patients | 350 | 328 | 22 | |
| Categories | .74 | |||
| Normal to mild | 74.0% | 74.1% | 72.7% | |
| Mild to moderate or reduced | 22.6% | 22.6% | 22.7% | |
| Severely reduced | 3.4% | 3.4% | 4.5% | |
| Tricuspid regurgitation closest before mitral procedure | ||||
| Number of patients | 352 | 330 | 222 | |
| Categories | .04 | |||
| None, trace, or mild | 79.3% | 80.6% | 59.1% | |
| Mild-to-moderate or moderate | 15.6% | 14.5% | 31.8% | |
| Moderate-to-severe or severe | 5.1% | 4.8% | 9.1% |
MR, Mitral regurgitation; SD, standard deviation; STS, Society of Thoracic Surgeons; LVEF, left ventricular ejection fraction; EF, ejection fraction; LVIDd, left ventricular internal diameter end diastole; LA, left atrial; SMVr, surgical mitral valve repair.