Table E4.
Baseline characteristics for patients who underwent TEER stratified by follow-up MR ≤1.5 versus ≥2.0 within 1 year of procedure
| Overall | MR ≤1.5, n = 199 | MR ≥2.0, n = 68 | P value | |
|---|---|---|---|---|
| Age, y | 73.6 ± 13.6 | 73.7 ± 12.7 | 73.1 ± 16.0 | .76 |
| Sex (male) | 61.8% | 60.8% | 64.7% | .57 |
| Hypertension | 86.1% | 87.4% | 82.4% | .30 |
| Hyperlipidemia | 75.7% | 78.9% | 66.2% | .04 |
| Diabetes | 36.0% | 40.7% | 22.1% | .006 |
| Depression history | 30.7% | 33.2% | 23.5% | .14 |
| Previous myocardial infarction | 18.0% | 17.1% | 20.6% | .52 |
| Coronary artery disease | 76.4% | 76.9% | 75.0% | .75 |
| Heart failure | 86.9% | 87.4% | 85.3% | .65 |
| Previous percutaneous coronary intervention | 17.6% | 18.6% | 14.7% | .47 |
| Previous coronary artery bypass graft | 8.2% | 9.0% | 5.9% | .61 |
| Previous stroke | 10.9% | 14.1% | 1.5% | .003 |
| Previous transient ischemic attack | 13.1% | 14.6% | 8.8% | .23 |
| Atrial fibrillation history | 68.9% | 68.3% | 70.6% | .73 |
| Atrial flutter history | 29.2% | 29.6% | 27.9% | .79 |
| Implantable cardioverter defibrillator | 15.0% | 14.1% | 17.6% | .48 |
| Pacemaker | 17.2% | 18.6% | 13.2% | .31 |
| Body mass index, kg/m2 | ||||
| Mean ± SD | 26.8 ± 6.2 | 27.6 ± 6.4 | 24.8 ± 4.9 | .001 |
| Category | .007 | |||
| <25.0 | 44.9% | 39.7% | 60.3% | |
| 25-29.9 | 30.7% | 32.2% | 26.5% | |
| ≥30 | 24.3% | 28.1% | 13.2% | |
| STS predicted risk of mortality score (%), n = 4 | 4.3 ± 2.1 | 4.7 ± 2.3 (n = 3) | 3.0 (n = 1) | .60 |
| LVEF closest before mitral procedure | ||||
| Number of patients | 257 | 194 | 63 | |
| Days, median (range) | 15.5 (1, 3660) | 18 (1, 2275) | 13 (1, 3660) | .19 |
| EF | 49.1 ± 15.8 | 49.6 ± 15.8 | 47.6 ± 15.7 | .38 |
| LVIDd closest before mitral procedure | ||||
| Number of patients | 252 | 190 | 62 | |
| Days, median (range) | 30.5 (1, 3660) | 33 (1, 3256) | 22 (1, 3660) | .01 |
| LVIDd | 5.3 ± 1.0 | 5.3 ± 1.0 | 5.4 ± 1.2 | .27 |
| LA size closest prior to mitral procedure | ||||
| Number of patients | 204 | 159 | 45 | |
| Days, median (range) | 40.5 (1, 4293) | 39 (1, 4160) | 43 (1, 4293) | .99 |
| Categories | .13 | |||
| 0 | 8.8% | 9.4% | 6.7% | |
| 1.0 | 12.3% | 10.1% | 20.0% | |
| 1.5 | 9.8% | 9.4% | 11.1% | |
| 2.0 | 18.6% | 18.9% | 17.8% | |
| 2.5 | 5.4% | 3.8% | 11.1% | |
| 3.0 | 45.1% | 48.4% | 33.3% | |
| Right ventricular size closest before mitral procedure | ||||
| Number of patients | 248 | 187 | 61 | |
| Categories | .52 | |||
| Normal to mild | 73.4% | 74.3% | 70.5% | |
| Moderate | 19.8% | 18.2% | 24.6% | |
| Severe | 6.9% | 7.5% | 4.9% | |
| Right ventricular function closest prior to mitral procedure | ||||
| Number of patients | 248 | 187 | 61 | |
| Categories | .70 | |||
| Normal to mild | 61.0% | 57.4% | 60.1% | |
| Mild to moderate or reduced | 38.0% | 41.0% | 38.7% | |
| Severely reduced | 1.1% | 1.6% | 1.2% | |
| Tricuspid regurgitation closest before mitral procedure | ||||
| Number of patients | 248 | 187 | 61 | |
| Categories | .11 | |||
| None, trace, or mild | 52.4% | 52.9% | 50.8% | |
| Mild-to-moderate or moderate | 35.5% | 37.4% | 29.5% | |
| Moderate-to-severe or severe | 12.1% | 9.6% | 19.7% |
MR, Mitral regurgitation; SD, standard deviation; STS, Society of Thoracic Surgeons; LVEF, left ventricular ejection fraction; EF, ejection fraction; LVIDd, left ventricular internal diameter end diastole; LA, left atrial; TEER, transcatheter edge-to-edge mitral valve repair.