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. 2024 Jan 8;24:16. doi: 10.1186/s12893-024-02313-6

Table 3.

Univariate analysis of risk factors for death from other diseases

Variables Number of patients Incidence rate of DOD (%) P value
5-year 10-year
Age (years) < 0.001
 < 70 529   2.6   8.2
 ≥ 70 281 15.3 32.5
Gender    0.233
 Male 587   7.5 17.9
 Female 223   5.8 12.8
Performance status (ECOG) < 0.001
 0 679   3.8 10.9
 1/2/3 131 23.7 44.6
Body mass index (kg/m2)    0.019
 < 22.0 334   8.7 21.3
 ≥ 22.0 476   5.9 13.1
Charlson Comorbidity Index score < 0.001
 0 542   2.5   9.3
 1/2 232 13.8 25.8
 ≥ 3   36 33.3 64.1
Cardiovascular disease < 0.001
 Absent 749   6.4 15.3
 Present   61 14.8 32.0
Respiratory disease < 0.001
 Absent 756   6.1 15.0
 Present   54 20.4 38.4
Renal disease < 0.001
 Absent 775   5.5 14.3
 Present   35 40.0 63.1
Liver disease    0.033
 Absent 775   6.5 15.8
 Present   35 20.0 31.7
Endocrine and collagen disease    0.006
 Absent 711   6.2 15.3
 Present   99 13.1 25.1
Neurological disease < 0.001
 Absent 759   6.2 15.2
 Present   51 19.6 37.5
Type of gastrectomy < 0.001
 TG 225 10.2 24.1
 DG/PG/PPG 585   5.8 13.6
Lymphadenectomy < 0.001
 D1/1+ 446 10.3 22.0
 D2/3 364   3.0 10.0
Combined resection    0.122
 Absent 700   7.4 16.4
 Present 110   4.5 16.7
Postoperative stay in hospital (days)    0.001
 < 20 450   5.3 12.3
 ≥ 20 360   9.2 21.5
Operative time (min.)    0.044
 < 250 337 11.0 21.0
 ≥ 250 473   4.2 13.2
Blood loss (mL)    0.813
 < 250 422   7.6 15.6
 ≥ 250 388   6.4 17.1
Postoperative complications* < 0.001
 Absent 602   5.2 12.9
 Present 208 12.5 27.2
Pathological stage†    0.002
 pStage I 661   5.4 14.3
 pStage II/III 149 14.1 26.1

*Grade II or higher according to the Clavien‒Dindo classification system

†Japanese classification of gastric carcinoma: 3rd English edition

DOD, death from other diseases; TG, total gastrectomy; DG, distal gastrectomy; PG, proximal gastrectomy; PPG, pylorus preserving gastrectomy