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. Author manuscript; available in PMC: 2024 Jan 9.
Published in final edited form as: Psychopharmacology (Berl). 2023 Jun 21;240(7):1561–1571. doi: 10.1007/s00213-023-06390-y

Figure 5.

Figure 5.

Mean (±SEM) changes in NAc oxygen levels induced by heroin (600 ug/kg) and its mixture with xylazine (600 ug/kg + 1 mg/kg) in freely moving rats. A = mean (±SEM) changes assessed with slow (1-min) time resolution. B = mean (±SEM) changes assessed with rapid (10-s) time resolution. Filled symbols show values significantly different from pre-injection baseline. n = numbers of averaged responses. Bold horizontal lines with asterisk show time intervals, during which between-group values were significant.