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. Author manuscript; available in PMC: 2024 Jan 9.
Published in final edited form as: Am J Physiol Heart Circ Physiol. 2002 Jun;282(6):H2183–H2189. doi: 10.1152/ajpheart.00964.2001

Fig. 1.

Fig. 1.

Concentration-dependent coronary vascular effects of adenosine (A), 2-[p-(2-carboxyethyl)]phenylethylamino-5′-N-ethylcarboxyamido-adenosine (CGS-21680) (B), and 2-chloro-N6-(3-iodobenzyl)-adenosine-5′-N-methyluronamide (Cl-IB-MECA) (C) in isolated hearts from both wild-type (WT) and A3 receptor knockout (A3KO) mice. Symbols represent means ± SE of 5–8 experiments. Concentration-response curve for coronary flow was constructed noncumulatively. y-Axis, changes in the coronary flow are expressed as %change from immediate baseline value that was assigned as 100%; x-axis, the molar concentration of agonists on a logarithmic scale. *P < 0.05 vs. corresponding WT value.