Fig. 2.
Influence of selective blockade of adenosine A3 receptor with 9-chloro-2-(2-furyl)-5-phenylacetylamino(1,2,4)-triazolo(1,5-c)quinazoline (MRS-1220) on CGS-21680-induced increases in coronary flow in WT mice. Control response to CGS-21680 (100 nM) was first determined in the absence of MRS-1220. After 10-min drug-free washout, hearts were pretreated with MRS-1220 (5 nM) for 15 min before second exposure to CGS-21680. Bars represent means ± SE of 6 experiments from different hearts in a paired manner. Vehicle control experiments were done in four hearts. *P < 0.05 vs. respective control value.