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. 2015 May 12;2015(5):CD010180. doi: 10.1002/14651858.CD010180.pub2
Study Reason for exclusion
Akahoshi 2002 Design: retrospective case series.
Bazeed 2013 Randomised trial of cyanoacrylate vs. ethanolamine in gastric varices.
Conference abstract. Not published article. Author contacted October 2014. Several emails were exchanged to gather further information.
Randomisation by envelopes, without random sequence generation. Unbalanced results of randomisation: 36 to cyanoacrylate, 69 to ethanolamine without explanation.
23 participants randomised to ethanolamine were treated with cyanoacrylate within 1 week. Total time of follow‐up was 1 week.
Huang 2000 Not a clinical trial but a case series with a long follow‐up.
Kim 2006 Not a clinical trial but an 86‐participant case series.
Ljubicic 2011 Randomised clinical trial of N‐butyl‐2‐cyanoacrylate for oesophageal and not gastric varices.
Maluf‐Filho 2001 Mechanisms of action, indications, technique, and results of N‐butyl‐2‐cyanoacrylate endoscopic injection in the treatment of oesophageal varices, and not gastric varices.
Maluf‐Filho 2008 Not a clinical trial, but a 48‐participant case series.
Mishra 2010 Different objectives: secondary prophylaxis. All the acute bleeding was treated with the same cyanoacrylate.
Mishra 2011 Different objectives: primary prophylaxis.
Ogawa 1999 It is not a clinical trial, a 38‐participant case series of cyanoacrylate or ethanolamine.
Oho 1995 Not randomised clinical trial.
Santos 2011 Different objectives. Oesophageal varices, not gastric varices.
Shiha 2010 Randomised trial of cyanoacrylate vs band ligation in gastric varices.
Conference abstract. No published article available. Several attempts to contact authors between October and December 2014 but we received no replies.
Results were expressed by significance, no actual numbers available. Percentages only available for 1 result (active bleeding).
Sugimoto 2007 Not a clinical trial but a small case series.
Thakeb 1995 Only 12% of the treated varices were gastric, with oesophageal varices being the remaining 88%.