Fig. 4.

Clustering of MTF-1 activating chemicals based on structural features. (A) Dendrogram focusing on those chemicals that were clustered into groups with at least three members. The dashed vertical line represents the similarity cut off used by the ChemmineR package to generate the chemical clusters, i.e. any splits that appear to the right of the dashed line are ignored when generating the clusters. (B) The structures of the chemicals found in Cluster 25 and Cluster 125 (indicated in red).