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. Author manuscript; available in PMC: 2024 Jan 27.
Published in final edited form as: J Leukoc Biol. 2023 Jul 27;114(2):142–153. doi: 10.1093/jleuko/qiad045

Table 2.

Self-reported non-injection drug use characteristics, drug treatment program history, and urine toxicology results (n = 97).

Non-injectors (n = 50)
Injectors (n = 47)
Injectors vs Non-injectors
Variable HIV (n = 14) HIV+ (n = 36) P HIV (n = 35) HIV+ (n= 12) P P

Self-reported NID use
 NIDs used in the past year 6 (43%) 14 (39%) 0.7466 27 (77%) 7 (58%) 0.2687 0.0020
  Alcohol 6 (l00%) 13 (93%) >0.9999 20 (74%) 5 (71%) >0.9999 0.0719
  Marijuana 0 (0%) 4 (29%) 0.2675 9 (33%) 1 (14%) 0.6445 0.5326
  Crystal meth 0 (0%) 4 (29%) 0.2675 13 (48%) 2 (29%) 0.4263 0.0862
  Cocaine 1 (17%) 4 (29%) >0.9999 13 (48%) 3 (43%) >0.9999 0.1511
  Downers 0 (0%) 0 (0%) >0.9999 5 (19%) 1 (14%) >0.9999 0.0740
  MDMA/ecstasy 0 (0%) 0 (0%) >0.9999 7 (26%) 1 (14%) >0.9999 0.0201
  Heroin 1 (7%) 0 (0%) 0.3000 1 (4%) 1 (14%) 0.3845 >0.9999
  Xylazine 0 (0%) 0 (0%) >0.9999 4 (15%) 0 (0%) 0.5585 0.2845
  Buprenorphine 6 (100%) 5 (36%) 0.0141 9 (33%) 2 (29%) >0.9999 0.1521
 # NIDs used 2 (0) 2 (1.75) 0.4989 3 (2) 2 (2) 0.3515 0.2407
Drug treatment history
 Ever 0 (0%) 12 (33%) 0.0215 30 (86%) 11 (92%) >0.9999 <0.0001
  In the past year 0 (0%) 3 (25%) >0.9999 18 (60%) 9 (82%) 0.2753 0.0195
Urine toxicology
 Urine test positive 2 (14%) 28 (78%) <0.0001 34 (97%) 11 (92%) 0.4496 <0.0001
  Multidrug positive 0 (0%) 15 (54%) 0.4828 28 (82%) 7 (64%) 0.2279 0.0233
  Fentanyl 0 (0%) 0 (0%) >0.9999 21 (62%) 4 (36%) 0.1757 <0.0001
  Cocaine 0 (0%) 6 (21%) >0.9999 19 (56%) 5 (45%) 0.7302 0.0044
  Opiates 0 (0%) 0 (0%) >0.9999 15 (44%) 4 (36%) 0.7363 <0.0001
  Benzodiazepines 0 (0%) 13 (46%) 0.4920 10 (29%) 2 (18%) 0.6991 0.1444
  Methadone 0 (0%) 2 (7%) >0.9999 18 (53%) 7 (64%) 0.7295 <0.0001
  Marijuana 2 (100%) 13 (46%) 0.4828 13 (38%) 3 (27%) 0.7202 0.2393
  TCAs 0 (0%) 5 (18%) >0.9999 6 (18%) 0 (0%) 0.3111 0.7461
  Amphetamine 0 (0%) 2 (7%) >0.9999 5 (15%) 0 (0%) 0.3131 0.6952
  Oxycodone 0 (0%) 1 (4%) >0.9999 0 (0%) 0 (0%) >0.9999 0.4000
  Barbiturates 0 (0%) 1 (4%) >0.9999 0 (0%) 0 (0%) >0.9999 0.4000
  Buprenorphine 0 (0%) 1 (4%) >0.9999 0 (0%) 4 (36%) 0.0022 0.6424
# positive drugs in urine 0 (0) 1 (1) <0.0001 3 (2) 2 (2.5) 0.2390 <0.0001

Continuous variables are shown as median with interquartile range and compared using Mann-Whitney tests. Categorical data are shown as counts with percentages (%) and compared using Fisher’s exact tests. The P values are italicized and significant P values are bolded.

NID, non-injection drug; TCA, tricyclic antidepressant.