Table 3.

Comparison of information density and required sequencing depth to prior work.

Study	Data encoded	Synthesis	Error correcting	Sequencing platform	Physical redundancy	Information density (bits/bp)
Church et al. [3]	650 kB	Phosphoramodite	High coverage	Illumina	3000×	0.6
Goldman et al. [10]	630 kB	Phosphoramodite	Multiply copies	Illumina	51×	0.19
Grass et al. [14]	80 kB	Phosphoramodite	RS + RS	Illumina	372×	0.86
Bornholt et al. [34]	151 kB	Phosphoramodite	Huffman code	Illumina	128×	0.57
Blawat et al. [25]	22 MB	Phosphoramodite	RS + BCH + CRC16	Illumina	160×	0.89
Erlich et al. [35]	2 MB	Phosphoramodite	Fountain + RS	Illumina	10.5×	1.19
Yazdi et al. [36]	3 kB	Phosphoramodite	MSA	ONT	200×	1.71
Organick et al. [8]	33 kB	Phosphoramodite	RS + RS	ONT	36×	0.81
Organick et al. [8]	200 MB	Phosphoramodite	RS + RS	Illumina	5×	0.81
Lee et al. [37]	96 B	Enzymatic	RS + BCH	ONT	175×	1.57
Chandak et al. [38]	11 kB	Phosphoramodite	Convolution + RS	ONT	14×	0.56
Meiser et al. [6]	176 kB	Phosphoramodite	RS + RS	Illumina	200×	0.85
Press et al. [15]	2 MB	Phosphoramodite	Hash + RS	Illumina	50×	1.2
Weigang et al. [39]	37.8 kB	Phosphoramodite	LDPC	ONT	16.8×	1.19
Lifu et al. [11]	6.8 MB	Phosphoramodite	Fountain + CRC	Illumina	–	1.3
This work	5.2 MB	Phosphoramodite	RS + CRC	Illumina	4×	1.37
This work	5.2 MB	Phosphoramodite	RS + CRC	ONT	8×	1.56

‘–’, denotes not available.