Table 2.
Disorder | n | Deeplasia w.r.t. two raters (months) | Deeplasia w.r.t. a single rater (months) | Inter-rater error (months) | |||
---|---|---|---|---|---|---|---|
MAD | RMSE | MAD | RMSE | MAD | RMSE | ||
ACh | 25 | 7.3 | 9.2 ([7.2, 12.7]) | 10.0 | 13.1 ([10.9, 16.2]) | 13.3 | 18.5 ([14.5, 25.5]) |
HyCh | 44 | 7.2 | 9.5 ([7.9, 12.0]) | 8.4 | 11.8 ([10.3, 13.9]) | 11.6 | 13.9 ([11.5, 17.6]) |
Noonan | 80 | 4.3 | 5.6 ([4.8, 6.6]) | 7.5 | 8.0 ([7.2, 9.0]) | 8.9 | 11.5 ([9.9, 13.6]) |
PsHPT | 30 | 7.5 | 8.8 ([7.1, 11.8]) | 10.3 | 13.9 ([11.8, 17.0]) | 13.9 | 21.5 ([17.2, 28.7]) |
SHOX mutation | 198 | 5.9 | 7.5 ([6.8, 8.3]) | 7.5 | 9.6 ([9.0, 10.3]) | 9.5 | 12.0 ([11.0, 13.4]) |
Silver-Russell | 69 | 6.2 | 7.7 ([6.6, 9.2]) | 7.7 | 9.6 ([8.6, 10.8]) | 7.7 | 11.5 ([9.8, 13.8]) |
Ullrich-Turner | 122 | 5.2 | 6.9 ([6.1, 7.9]) | 6.4 | 8.7 ([8.0, 9.6]) | 8.4 | 11.5 ([9.6, 12.3]) |
IUGR | 55 | 7.2 | 8.9 ([7.5, 11.0]) | 8.8 | 10.8 ([9.6, 12.5]) | 8.5 | 12.2 ([10.3, 15.0]) |
None diagnosed | 79 | 6.3 | 8.1 ([7.0, 9.6]) | 9.3 | 10.5 ([9.5, 11.8]) | 10.0 | 13.5 ([11.6, 15.9]) |
Accuracy is shown with respect to the average bone age rating of two raters (columns 3 and 4) and a single rater (columns 5 and 6), plus the inter-rater errors (columns 7 and 8), lower MAD and RMSE errors mean higher accuracy. n refers to the number of individual radiographs per disorder. The RMSE is stated with the 95% confidence interval. ACh achondroplasia, GDBD German Dysplastic Bone Dataset, HyCh hypochondroplasia, IUGR intrauterine growth restriction, MAD mean absolute difference, PsHPT pseudohypoparathyroidism, RMSE root mean squared error, w.r.t with respect to