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. 2024 Jan 9;15(1):18. doi: 10.1038/s41419-023-06299-6

Fig. 4. Analysis of DLBCL survival in 3D alginate + RGD Vitrogel spheroids after 24-h incubation.

Fig. 4

A Viability of DLBCL in spheroids loaded at ≤2 cells/mm3. N: Media = 150, CHOP = 59, Rituximab = 54, NK = 149, NK+r = 120 and NK+rCHOP = 150 spheroids. B Comparison of DLBCL survival across treatment conditions in low-density versus high-density spheroids, normalized to media-only control. N of high-density experiments: Media = 72, CHOP = 89, Rituximab = 72, rCHOP = 88, NK = 35, NK+r = 46 and NK+rCHOP = 37 spheroids. Statistical analysis based on one-way ANOVA with Tukey multiple-comparisons test. Error bars represent 95% confidence interval of mean. *P ¬<0.05, **P < 0.01, ***P < 0.001 ****P < 0.0001.