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. 2024 Jan 10;14:939. doi: 10.1038/s41598-024-51383-2

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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(A) Comparison of serum galectin-3 levels between HD patients and healthy controls. The mean serum galectin-3 levels of HD patients were significantly higher than those of healthy controls (p < 0.001). (B) Receiver operating characteristic curve (ROC) analysis of the prediction of mortality by serum galectin-3 levels. At a cut-off value of 37.0 ng/mL of serum galectin-3, the AUC for predicting mortality was 0.718 with sensitivity and specificity of 60.2% and 74.7%, respectively. PPV positive predictive value, NPV negative predictive value, AUC area under the ROC curve.