Table 4.
Multivariate analysis predicting the risk of mortality with aortic calcification and higher galectin levels (≥ 37.0 ng/mL).
| All-cause mortality | ||||
|---|---|---|---|---|
| Univariate analysis | Multivariate analysis* | |||
| HR (95% CI) | p | HR (95% CI) | p | |
| Age | 1.07 (1.05–1.09) | < 0.001 | 1.05 (1.02–1.07) | 0.001 |
| Sex, male | 0.92 (0.66–1.28) | 0.626 | – | – |
| CVC use | 3.26 (2.30–4.61) | < 0.001 | 3.27 (1.78–6.03) | < 0.001 |
| CAD, history | 1.60 (1.13–2.27) | 0.008 | 0.73 (0.40–1.33) | 0.301 |
| Diabetes | 1.03 (0.74–1.45) | 0.860 | – | – |
| Albumin < 3.5 g/dL | 1.60 (1.14–2.24) | 0.006 | 1.13 (0.67–1.89) | 0.652 |
| Phosphate ≥ 5.0 mg/dL | 0.74 (0.53–1.03) | 0.101 | – | – |
| hsCRP ≥ 1.0 mg/L | 2.32 (1.48–3.65) | < 0.001 | 1.49 (1.02–2.59) | 0.046 |
| HDL-C mg/dL | 0.98 (0.97–0.99) | 0.032 | 1.00 (0.98–1.02) | 0.704 |
| BNP ≥ 1200 mmol/L | 1.67 (1.14–2.44) | 0.008 | 1.27 (0.72–2.26) | 0.410 |
| Galectin-3 ≥ 37 ng/mL | 3.08 (2.20–4.32) | < 0.001 | 1.71 (1.02–2.92) | 0.048 |
| AoAC | ||||
| 0 | Reference | Reference | ||
| 1 | 1.34 (0.83–2.16) | 0.227 | 1.34 (0.65–2.78) | 0.434 |
| 2 | 2.37 (1.51–3.73) | < 0.001 | 1.81 (0.92–3.91) | 0.127 |
| 3 | 7.48 (4.81–11.62) | < 0.001 | 1.98 (1.01–4.00) | 0.049 |
CVC central venous catheter, CAD coronary artery disease, HDL high density lipoprotein, hsCRP high-sensitivity C-reactive protein, BNP brain-natriuretic peptide, AoAC aortic arch calcification.