2.

Immediate insertion compared with standard insertion for postpartum IUC
Patient or population: postpartum women with desire for contraceptive Setting: hospital or clinic Intervention: immediate postplacental insertion (within 10 minutes) Comparison: standard insertion (at postpartum visit)
Outcomes	Relative effect (95% CI)	Participants (studies)	Quality of the evidence (GRADE)
Placement per protocol	OR 4.07 (95% CI 0.54 to 30.40); I2 = 68%	243 (4 studies)	⊕⊕⊕⊝ Moderate
Expulsion by 6 months	OR 4.89 (95% CI 1.47 to 16.32)	210 (4 studies)	⊕⊕⊕⊝ Moderate
IUC use at 6 months	OR 2.04 (95% CI 1.01 to 4.09)	243 (4 studies)	⊕⊕⊕⊝ Moderate
CI: Confidence interval; OR: Odds ratio
GRADE Working Group grades of evidence High quality: Further research is very unlikely to change our confidence in the estimate of effect. Moderate quality: Further research is likely to have an important impact on our confidence in the estimate of effect and may change the estimate. Low quality: Further research is very likely to have an important impact on our confidence in the estimate of effect and is likely to change the estimate. Very low quality: We are very uncertain about the estimate.