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. 2023 Nov 24;120(47):797–803. doi: 10.3238/arztebl.m2023.0208

Table 1. Areas of indication and types of application of digital health applications (DiGA) (excerpt: Indication Depression, eTable 1).

Deprexis Selfapy’s online course for depression Novego:
Coping with depression
Edupression.com Elona therapy Depression
Type of application
Web application*1 Web application*1
+ Smartphone app*2
Web application*1 Web application*1 Web application*1
+ Smartphone app*2
Listing status
Final Final 10.10.2021–09.10.2022*3 26.12.2022–25.08.2022*3 26.12.2022–25.12.2023*3
Indications
● Mild to severe depressive episode (F32.0, F32.1, F32.2)
● Recurrent depressive disorder (F33.0, F33.1, F33.2)
● Mild and moderate depressive episode (F32.0, F32.1)
● Recurrent depressive disorder (F33.0, F33.1)
● Mild and moderate depressive episode (F32.0, F32.1)
● Recurrent depressive disorder (F33.0, F33.1)
● Dysthymia (F34.1)
● Mild and moderate depressive episode (F32.0, F32.1)
● Recurrent depressive disorder (F33.0, F33.1)
● Mild and moderate depressive episode (F32.0, F32.1)
● Recurrent depressive disorder (F33.0, F33.1)
● Dysthymia (F34.1)
Contraindications
● Schizophrenia (F20)
● Acute transient psychotic disorder (F23)
● Schizoaffective disorders (F25)
● Bipolar disorder (F31)
● Other symptoms and signs involving emotional state (R45.8)
● Suicidal risk
● Alzheimer dementia (F00)
● Alcohol dependence and withdrawal syndrome (F10.2, F10.3)
● Schizophrenia (F20)
● Bipolar disorder (F31)
● Severe depressive episode with psychotic symptoms (F32.3, F33.3)
● Acute suicidality
● Organic mental disorder (F0x)
● Dependence disorder (F1x.2)
● Psychotic disorder (F2x)
● Bipolar disorder (F31)
● Mania (F30.0)
● Suicidality in the last 4 weeks
● Schizotypal disorder (F21)
● Persistent delusional disorders(F22)
● Bipolar disorder (F31)
● Severe depressive episode with psychotic symptoms (F32.3, F33.3)
● Suicidality
● Psychotic disorder (F2x)
● Psychotic disorder (F2x)
● Bipolar disorder (F31)
● Mania (F30)
● Severe depressive episode with psychotic symptoms (F32.3, F33.3)
● Acute suicidality
Duration of use
At least 90 days
(1–2 x/week minimum duration 30 min each)
At least 90 days At least 90 days At least 90 days At least 90 days
Costs/quarter (€)
210.00 217.18 249.00 357.00
(follow-up prescription: 178.50)
535.49
Foreign languages
ELL, ENG, FRA, ITA, POR, SPA, SWE, ZHO ENG

*1 Web application (internet-enabled end device)

*2 Smartphone app (Android/ iOS smartphone)

*3 In case of provisional listing in the BfArM‘s DiGA Directory, the trial period is stated.

ELL, Greek; ENG, English; FRA, French; ITA, Italian; POR, Portuguese; SPA, Spanish; SWE, Swedish; ZHO, Chinese