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Biogenesis of exosomes. Exosomes are derived from the fusion of MVBs. Exosomes can transport nucleic acids, proteins and lipids to recipient cells from doner cells to recipient cells mainly through receptor-ligand interaction, membrane fusion and endocytosis. By Figdraw (https://www.figdraw.com/#/). MVB, multivesicular body; circRNA, circular RNA; lncRNA, long non-coding RNA; miRNA, microRNA; ESCRT, endosomal sorting complex required for transport.
