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. 2023 Dec 27;14:1291965. doi: 10.3389/fphar.2023.1291965

TABLE 4.

Molecular docking scores of ChV’s bioactive compounds on Japanese quails’ IL1RAP, IL6RA, TNFRSF1A, and TRAF1.

Compound Molecular docking score (kcal/mol)
IL1RAP IL6RA TNFRSF1A TRAF1
7-Hydroxyflavanone −6.28 −5.47 −4.96 −4.76
Benzoic acid −4.79 −4.49 −4.16 −3.97
Caffeic acid −5.40 −4.91 −4.41 −4.59
Catechin −6.95 −5.60 −4.96 −5.53
Catechol −5.00 −4.28 −4.02 −3.66
Chlorogenic acid −8.19 −6.29 −6.14 −5.90
Cinnamic acid −5.11 −4.73 −4.13 −4.23
cis-Phytoene −9.71 −8.46 −7.80 −7.30
Ellagic acid −6.70 −5.78 −5.11 −5.04
Gallic acid −5.44 −4.92 −4.49 −4.08
Hesperidin −10.19 −7.67 −7.14 −7.11
Kaempferol −8.52 −8.46 −8.08 −6.77
Loroxanthin −8.90 −7.91 −7.63 −6.33
Luteolin −6.82 −5.86 −5.07 −5.01
Naringin −10.21 −8.43 −7.10 −7.01
Phytofluene −10.23 −8.48 −7.36 −6.69
Pyrogallol −5.12 −4.22 −3.97 −3.82
Quercetin −7.00 −6.16 −4.89 −5.40
Rutin −9.17 −8.48 −7.55 −6.97
Salicylic acid −5.46 −4.64 −4.05 −3.96
Syringic acid −5.73 −5.10 −4.68 −4.66
Zeta-Carotene −9.74 −8.65 −7.35 −7.24
β-Carotene −9.23 −7.77 −7.01 −6.57

IL1RAP, interleukin-1 receptor accessory protein; IL6RA, interleukin-6 receptor subunit alpha; TNFRSF1A, tumor necrosis factor receptor superfamily member 1A; TRAF1, tumor necrosis factor receptor-associated factor 1.