Week 0		Week 8		Δ 0 to 8 weeks
Pain and Function Tests	N	Median (IQR) range	N	Median (IQR) range	Median (IQR) range	p-value
VAS	49	28 (18-37) 15-49	20	58.0 (40.0-71.5) 0-80.0	-0.5 (-9-11) -28.0-60.0	NS
PROMIS PI	49	61.7 (59.1-66.9) 50.1-77.8	23	63.9 (57.7-68.2) 47.1-76.4	-1.3 (-4.7-5.2) -10.9-14.3	NS
PROMIS PB	49	59.6 (57.5-61.9) 51.2-67.6	23	59.6 (57.4-62.6) 49.7-66.9	0.0 (-2.0-2.9) -6.3-10.4	NS
PROMIS PF	49	39.9 (38.0-44.0) 27.2-73.3	23	39.0 (30.9-41.7) 22.2-50.1	3.4 (-1.8-9.0) -17.6-23.2	0.031
HOOS	49	82.0 (63.0-93.0) 16.0-160.0	23	83.0 (58.0-105.0) 16.0-155.0	-2.0 (-15.0-17.0) -63.0-51.0	NS
Symptom	49	11.0 (9.0-13.0) 4.0-20.0	23	11.0 (9.0-14.0) 3.0-19.0	-1.0 (-2.0-2.0) -6.0-6.0	NS
Pain	49	19.0 (15.0-24.0) 2.0-40.0	23	21.0 (14.0-27.0) 3.0-40.0	-2.0 (-4.0-3.0) -19.0-24.0	NS
Function	49	26.0 (20.0-34.0) 1.0-68.0	23	36.0 (19.0-42.0) 0-68.0	0.0 (-7.0-5.0) -33.0-14.0	NS
Sport	49	10.0 (8.0-12.0) 2.0-16.0	23	11.0 (7.0-15.0) 2.0-16.0	-1.0 (-3.0-2.0) -5.0-13.0	NS
Psychological Tests
PCS	50	19.5 (13.0-28.0) 1-48.0	23	19.0 (9.0-24.0) 0-42.0	2.0 (-4.0-6.0) -23-26	NS
DASS
Stress	49	12.0 (8.0-20.0) 0-40.0	23	10.0 (6.0-16.0) 0-40.0	2.0 (-4.0-4.0) -18.0-26.0	NS
Anxiety	49	1.0 (0.0-5.0) 0.0-51.0	23	0.0 (0.0-2.0) 0.0-22.0	0.0 (0.0-2.0) -12.0-33.0	NS
Depression	50	2.0 (0.0-10.0) (0.0-51.0)	23	2.0 (0.0-6.0) 0.0-26.0	0.0 (-1.0-4.0) -18.0-41.0	NS
PROMIS GMH	49	47.7 (44.1-52.7) 25.8-64.6	23	46.3 (36.0-52.7) 25.8-64.6	0.0 (-6.3-8.1) -14.6-14.9	NS
AUDIT	49	2.0 (0.0-5.0) 0.0-11.0	23	1.0 (0.0-4.0) 0.0-10.0	0.0 (0.0-1.0) -5.0-4.0	NS
BRS	32	3.6 (2.9-4.0) 1.8-5.0	19	3.8 (3.2-4.2) 2.0-5.0	-0.2 (-0.3-0.0) -1.8-0.7	NS
GSE	48	30 (29-36) 14 - 40	22	32 (30-38) 21-40	0 (-3-1) -12-6	NS
Grit-S	47	3.9 (3.4-4.3) 2.3-4.8	21	4.0 (3.6-4.1) 2.8-4.8	0.0 (-0.4-0.1) -2.0-0.6	NS
TSK	48	29.0 (26.5-31.5) 11.0-40.0	21	27.0 (24.0-33.0) 11.0-39.0	1.0 (-1.0-3.0) -8.0-17.0	NS

NS= not significant.