Effects of adding to Trg the 19-residue, carboxy-terminal tail of Tsr. Tar, Trg, and the hybrid receptor Trgt were tested for methyl-accepting activity (A) and kinase activation (B) as described in the legends to Fig. 4 and 2, respectively. Methylation rates were determined after a 1-min incubation and were expressed as a percentage relative to the rate for Tar. Kinase activation was expressed as a percentage relative to the Trg-mediated value. The data are averages from two independent experiments, and the error bars show standard errors.