TABLE 3.

H1N1 viral load in apical wash from ALI nasal epithelium treated with Apilimod or oseltamivir

		Hour post-H1N1 inoculation (Log, pfu/mL: geometric mean ± SD, n = 3)
		24 hours	48 hours
Vehicle (H2O)	Apical	2.9 ± 0.22	3.5 ± 0.39
Apilimod mesylate (0.2 mg/mL)	Apical	2.7 ± 0.30	2.9 ± 0.32
Apilimod mesylate (2 mg/mL)	Apical	2.2 ± 0.16 b	2.0 ± 0.14 b
Oseltamivir carboxylate (0.2 mg/mL)	Basal	2.1 ± 0.10 b	2.1 ± 0.20 b

^a Changes in each group were compared to virus-infected epithelium treated with the vehicle using Dunnett’s one-way analysis of variance.

^b P < 0.05.