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. 2023 Dec 20;16(1):39. doi: 10.3390/cancers16010039
CAR Chimeric antigen receptor
TME Tumor microenvironment
ACT Adoptive T-cell transfer
MHC Major histocompatibility complex
TAA Tumor-associated antigen
FasL Fas ligand
TRAIL Tumor necrosis factor-related apoptosis-inducing ligand
FDA The Food and Drug Administration
EMA The European Medicines Agency
EGFR Epidermal growth factor receptor
HER2 Human epidermal growth factor receptor 2
HNSCC Head and neck squamous cell carcinoma
CEA Carcinoembryonic antigen
PSMA Prostate-specific membrane antigen
scFv Single-chain variable fragment
CD Cluster of differentiation
NSCLC Non-small-cell lung cancers
OS Overall survival
PD-1 Programmed cell death-1
PFS Progression-free survival
CSD Co-stimulatory domain
IL Interleukin
CRISPR Clustered regularly interspaced short palindromic repeats
TCR T-cell receptor
CLL Chronic lymphocytic leukemia
ALL Acute lymphoblastic leukemia
DLBCL Diffuse large B-cell lymphoma
TNBC Triple-negative breast cancer
TLR4 Toll-like receptor 4
DCs Dendritic cells
DAMPs Damage-associated molecular patterns
HMGB1 High-mobility group box 1
IFN-I Type I interferon
Tregs Regulatory T cells
MDSC Myeloid-derived suppressor cells
TGF-β Transforming growth factor-Β
EOC Epithelial ovarian cancer
CTX Cyclophosphamide
M6P Mannose-6-phosphate
HLA Human leukocyte antigen
APCs Antigen-presenting cells
BCMA B-Cell maturation antigen
CPIs Checkpoint inhibitors
DNR PD-1 dominant negative receptor
shRNA Short hairpin RNA
A2ARs Adenosine 2A receptors
CTLA-4 Cytotoxic T-lymphocyte associated protein 4
PDCD1 Programmed cell death protein 1
TRAC T-Cell receptor alpha constant
BiTEs Bispecific T-Cell engager
HDAC Histone deacetylase