| Low Reactivity |
Reactants may not fully react,
resulting in a low yield of
the desired product. |
| Side Reactions |
Other thermodynamically possible reaction paths may be followed,
leading to side products and lower yield. |
| Reactant/Reagent/ Catalyst Deactivation |
Deactivation
of reactants, reagents, or catalysts caused by
other reaction system components. |
| Thermodynamic
and Kinetic Factors |
Reaction conditions (temperature,
pressure, concentration,
etc.) can affect the reaction rate and yield. |
| Contaminants |
Impurities in reactants or reagents can
interfere with the
reaction and reduce the yield. |
| Sensitivity
to Environment |
Reactions may be sensitive to environmental
factors like air,
moisture, or light. |
| Product Degradation/
Reactivity |
The desired product may be too reactive or
unstable, leading
to further reactions or degradation. |
| Product
Isolation |
Difficulties in isolation or purification
of the product can
result in a lower yield. |